DC-Research Knowledge Portal: poly(I:C) (Invivogen Life Technologies)

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Anne O'Garra

Executive Committee, Scientific responsible

MRC - The National Institute for Medical Research

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Macrophages and myeloid DC, but not plasmacytoi...

journal article

J.Immunol. 177, 7551 – 7558

Boonstra, A., Rajsbaum. R., Holman, M., Marques, R., Asselin-Paturel, C., Pereira, J.P., Bates, E.M., Akira, S., Vieira, P., Liu, Y-J., Trinchieri, G., and O’Garra,A

Bio Materials > molecular structure > Molecular entity > Polyinosinic acid:polycytidylic acid > poly(I:C) (Invivogen Life T...

poly(I:C) (Invivogen Life Technologies)

Polyinosinic acid:polycytidylic acid

The poly(I:C) was used for stimulating DCs. It was shown in mice that both IL-10 as well as IL-12 production is dependent on the signalling adaptor molecules either MyD88 or TRIF, respectively in response to CpG, LPS or PolyIC.

Manufacturer: Invivogen Life Technologies

created over 15 years ago (4 March 2009) last modified over 13 years ago (28 September 2011) [ RDF ] [ RelFinder ]


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